Biomek FXᴾ Automated Workstation

Flexibility for your high throughput workflow

Biomek FX^P provides the speed and performance critical to today’s research environments. The flexible platform is available in single and dual pipetting head models combining multichannel (96 or 384) and Span-8 pipetting. Ideal for high throughput workflows, Biomek FX^P accelerates laboratory processing, and is easy to update or integrate as your research needs evolve.

Features

Versatile Workspace

Up to 24 deck positions
Automated Labware Positioners (ALPs) for plate processing
Integrate third-party devices on- and off-deck
Configurable for specific applications

Flexible Pipetting and Workflow Management

Multiple single- and dual-arm configurations available using Multichannel heads (96/384/Pin tool) with gripper and/or Span-8 pipetting
Parallel processing on dual-arm systems
Disposable & fixed Biomek tips (including septum piercing)
Transfer volumes from 0.5 µL - 5,000 µL
8 channel liquid-level sensing
Supports labware from tubes to 1,536-well microplates
Accurate intra-well pipetting

Simple System Operation

Easily automate existing processes
Powered by icon-based software with data tracking & LIMS connectivity
Extend walkaway operation with process management & scheduling software
Guided system setup
Automated deck framing
Data-driven method operations including hit-picking & normalization
Light curtain safety feature

Application-focused Solutions

Consultative workflow analysis
Expert application and technical support
Biomek-automated demonstrated methods & capabilities for genomic, drug discovery & basic research workflows

Product Specifications

Minimum Table Support Requirements	92.00\|77.00\|cm (139.7 cm min height requirement)
Sterile	No

Operating System	Windows® 7
Software	Biomek software, SAMI EX scheduling software, Biomek PowerPack software, Biomek Method Launcher, DART 2.0 software
Display	22" controller screen
Operating Mode(s)	Semi-automated, manual, controlled by operator
Item Specifications Referenced	A31844

Documentation

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Title	Description
Automated XTT Assay for Cell Viability Analysis {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Cellular viability assays are valuable for numerous workflows—from establishing proliferation rates to drug toxicity screens.
A Fully-Automated, Image-Based Screen for miRNAs that Regulate Cancer Cell Viability and Chemosensitivity {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Michael Kowalski, Staff Applications Scientist, \| Beckman Coulter Life Sciences, Indianapolis, IN \| Tammy Chan, Field Application Scientist, \| Molecular Devices, Sunnyvale, CA \| Kristin Prasauckas, Manager, Field Applications Scientist, \| Molecular Devices, Sunnyvale, CA \|Tara Jones-Roe, Marketing Manager, \| Beckman Coulter Life Sciences, Indianapolis, IN
Automated FFPE DNA Extraction using the FormaPure DNA Extraction Kit using the Biomek Series of Automated Liquid Handlers from Beckman Coulter, Inc. {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Author: Zach Smith, M.S. \| Beckman Coulter, Inc. \| Published 2016
Automated DNA Library Construction using the NEBNext® Ultra II DNA Library Prep Kit for Illumina® on the Beckman Coulter Biomek FXP Automated Liquid Handler {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Zach Smith, M.S. \| Beckman Coulter, Inc. Daniela Munafo, Ph.D. \| New England Biolabs, Inc. Brad Langhorst, Ph.D. \| New England Biolabs, Inc. Laurie Mazzola \| New England Biolabs, Inc. Joanna Bybee \| New England Biolabs, Inc. Danielle Rivizzigno \| New England Biolabs, Inc. \| Published 2016
Automation of the Illumina® TruSeq® DNA PCR-Free Sample Preparation Kit on the Biomek FXP Automated Liquid Handler {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Author: Zach Smith, M.S. Beckman Coulter Life Sciences, Indianapolis, IN USA \| Published 2014
Automated Illumina TruSeq Custom Amplicon Low Input Library Preparation Kit on the Beckman Coulter Biomek FXP Automated Liquid Handler {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Author: Zach Smith, M.S. \| Beckman Coulter, Inc. \| Published 2016
Automated ELISAs—Save Time and Increase Throughput {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	We demonstrate how the integration of the MultiWash™+ Microplate Washer and EMax® Plus Microplate Reader to a Biomek NXP Workstation facilitates the automated processing and analysis of ELISAs.
Automated Optimization of Cell Transfection {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Here we demonstrate how the Biomek FXP Workstation can be used to identify the optimal conditions for siRNA transfection in a single experiment.
Automation of the Illumina® TruSeq® DNA PCR-Free Sample Preparation Kit on the Biomek FXP Automated Liquid Handler {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Author: Zach Smith, M.S.
Biomek Automated 384-well qPCR Setup using KAPA Biosystems Library Quantification Kit for Illumina Sequencing Platforms {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Library quantification is an essential step in the illumina next-generation sequencing(NGS) workflow
Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Author: Michael Kowalski, Staff Applications Scientist \| Beckman Coulter Life Sciences, Indianapolis, IN \| Published 2016
High-Throughput Illumina® TruSeq® Nano DNA Library Construction on the Biomek FXP Dual-Arm Multi-96 and Span-8 Workstation {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	The manual preparation of large numbers of sequencing libraries, which can be labor-intensive and time-consuming, is a bottleneck for many laboratories
Automated Solutions for Cellular Analysis Through Flow Cytometry {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Michael Kowalski - Staff Applications Scientist, Li Liu - Senior Development Scientist, Amy Yoder - Staff Development Scientist, Beckman Coulter Life Sciences, Indianapolis, IN \| Published 2014
Automated Optimization of Cell Transfection {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Demonstrated application on how the Biomek FXP Workstation can be used to identify the optimal conditions for siRNA transfection in a single experiment.
Illumina TruSight® HLA Sequencing Panel Automated on the Biomek FXP HLA SP Liquid Handler {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Zach Smith, MS, Senior Applications Scientist - Beckman Coulter, Inc. \| Nate Baird, PhD, Scientist, Illumina \| Brad Baas, PhD, Senior Scientist, Illumina \| Published 2015
Automated Optimization of IgG Production in CHO Cells {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Michael Kowalski, Staff Applications Scientist - Beckman Coulter Life Sciences, Indianapolis, IN \| David Apiyo, Marketing Applications Manager - Pall ForteBio, Fremont, CA \| Rashi Takkar, Product Manager - Pall ForteBio, Fremont, CA \| Tara Jones-Roe, Marketing Manager -Beckman Coulter Life Sciences, Indianapolis, IN
Automated DNA Library Construction Using the NEBNext® Ultra™ DNA Library Prep Kit for Illumina® on the Beckman Coulter Biomek FXP Automated Liquid Handler {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	We describe the automation of the New England Biolabs NEBNext Ultra DNA Library Preparation Kit for Illumina on the Beckman Coulter Biomek FXP Dual-Arm Multichannel 96 and Span-8 automated liquid handler (Biomek FXP ).
High-Capacity Next Generation Sequencing Platforms {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Meet the Demand of Illumina’s High-Capacity NGS Platforms with Biomek Automated Sample Preparation
Automating 3-D Cell Culture and Screening by Flow Cytometry and High-Content Imaging {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Author: Michael Kowalski, Ph.D. \| Staff applications scientist for Beckman Coulter Life Sciences Indianapolis, IN \| Published 2016
BeckmanConnect Security Highlights {749D68FB-4893-4B2D-BD6C-C662F0520F64}	This document highlights the privacy and security features in the BeckmanConnect remote management solution.
Beckman Coulter Instrument PC Networking Requirements {749D68FB-4893-4B2D-BD6C-C662F0520F64}	This document describes the minimum technical criteria required to connect a Beckman instrument PC to a customer’s local network and/or the internet.
Automating Biologics Signature Peptide Quantitation {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Ian Moore, Technical Marketing Manager \| SCIEX, Concord, Canada, Michael Kowalski, Staff Applications Scientist \| Beckman Coulter Life Sciences, Indianapolis, IN
Biomek FXP Laboratory Automation Workstation as a Tool for Discovering Targets & Compounds for Host-Directed Influenza Therapy {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Markus Lesch, Project Manager, Center for Systems Biomedicine, Steinbeis Innovation gGmbH. Falkensee, Germany, Alexander Karlas, Senior Scientist, Max Planck Institute for Infection Biology, Berlin, Germany. Published: 2015
Automated TruSeq RNA Sample Preparation from FFPE Tissue Specimens Utilizing the Biomek FXp Liquid Handler {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Bee Na Lee Ph.D., Senior Application Scientist, and Sarah Simons, Advanced Specialist- Field Systems Support, Beckman Coulter Life Sciences \| Michaela Bowden Ph.D., Research Scientist \| Ashley Rossi, Molecular Technician, and Ed Stack Ph.D., Associate Director Center for Molecular Oncologic Pathology, Medical Oncology at DFCI \| Svitlana Tyekucheva, Department of Biostatistics, DFCI Biostatistics & Computational Biology and Massimo Loda MD., Director Center for Molecular Oncologic Pathology, Medical Oncology at DFCI and Department of Pathology at Brigham and Women's Hospital
Automated Size Selection using SPRIselect Beads and the Biomek FX Liquid Handler {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Alexandre Bélisle, Vicky Arsenault, Belisle Tir, Alfredo Staffa Sylvie LaBoissière and Alexandre Montpetit - McGill University and Génome Québec Innovation Centre - Montréal, Québec, Canada
High Throughput TruSeq Stranded mRNA Library Construction on the Biomek FXP {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Zach Smith \| Scott D. Michaels \| Mary Blair
Automated Directional RNASeq Library Preparation using the Biomek FXP Liquid Handler {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	We describe the automation of the New England Biolabs NEBNext (Registered trademark) Ultra Directional RNA Library Prep Kit for Illumina on the Beckman Coulter Biomek FXP automated liquid handler.
Automated Cell Culture: Improving the Consistency of Cell Maintenance {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	In this application note, we illustrate the capabilities for automating a standard workflow for cell line maintenance and demonstrate this process using mouse embryonic stem cells.
Illumina TruSight® HLA Sequencing Panel Automated on the Biomek FXP HLA SP Liquid Handler {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	We describe the automation of the Illumina TruSight® HLA Sequencing Panel on the Beckman Coulter Biomek FXP HLA SP.
Automated TruSeq RNA Sample Preparation from FFPE tissue specimens utilizing the Biomek FXp Liquid Handler {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This application note describes automated RNA library construction using the Beckman Coulter Biomek FXP Liquid Handler from archival FFPE tissue specimens.
Automated Size Selection using SPRIselect beads and the Biomek FX Liquid Handler {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This application note describes the automation of the Size Selection using SPRIselect beads on the Biomek FX Liquid Handler.
Biomek ® FXP Laboratory Automation Workstation {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}	With an up-to-date hardware design for greater positional accuracy and increased robustness, it can meet the needs of just about any application.
Biomek-Automated NGS Library Construction Methods {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}	Next generation sequencing demonstrated methods
Lab Automation Training Programs {9E29D7A5-B5EC-470A-A5C1-4EF9BFAE9959}	Real-world training options for maximizing the value of your Biomek liquid handling system.
Protection for your Workflows in Automation {9E29D7A5-B5EC-470A-A5C1-4EF9BFAE9959}	Maintenance service plan for Biomek liquid handlers
BeckmanConnect Installation and Activation Instructions {B14306BD-BB46-4B27-BF3E-B11862085BC7}	A step-by-step guide to help you successfully install BeckmanConnect.
High Throughput TruSeq Stranded mRNA Library Construction on the Biomek FXP {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Zach Smith and Scott D. Michaels - The Center for Genomics and Bioinformatics - Indiana University \| Mary Blair - Life Science Division Beckman Coulter - Indianapolis, IN \| Published 2013
Automation and Miniaturization of 3D Tumor Models for Compound Screens {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	Authors: Michael Kowalski, Kayla Hill, Vipat Raksakulthai, Kristin Prasauckas, Tara Jones-Roe - Beckman Coulter Life Sciences, Indianapolis, IN Molecular Devices, Sunnyvale, CA
Automated NGS Sample Prep with Integrated Data Management and Reporting Tools {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	Authors: Zach Smith, M.S., John Snider, M.S., David Horvath, M.S.- Beckman Coulter Life Sciences \| Published 2015
Roche GS FLX Titanium Rapid Library Preparation Kit Automation Using Biomek® FXp Laboratory Automation Workstation {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	This poster presents the automated Roche GS FLX Titanium “Rapid Library Preparation Kit” using Beckman Coulter’s Biomek FXP dual hbrid laboratory automation workstation.
Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	Authors: Michael P. Kowalski , Vipat Raksakulthai, Kristin Prasauckas, Tara Jones-Roe - Beckman Coulter Life Sciences, Indianapolis, IN and Molecular Devices, Sunnyvale, CA
Roche GS FLX Titanium* Rapid Library Preparation Kit Automation Using Biomek® FXp Laboratory Automation Workstation {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	Authors: Ruth Zhang Ph.D. , Zach Smith , Laura Pajak Ph.D. , Keithanne Mockaitis, Ph.D. , John Colbourne Ph.D. , and Alisa Jackson - Beckman Coulter, Inc., Indianapolis, Indiana and The Center for Genomics and Bioinformatics, Indiana University, Bloomington, Indiana
Automated TruSeq RNA Sample Preparation from FFPE Tissue Specimens Utilizing the Biomek FXP Liquid Handler {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	Authors: Michaela Bowden Ph.D., Ashley Rossi, Bee Na Lee Ph.D., Sarah Simons Svitlana Tyekucheva, Ed Stack Ph.D., Massimo Loda MD., \| Dana Farber Cancer Institute and Brigham, Women’s Hospital and Beckman Coulter Life Sciences
Automation of a Cell-Based Screening Assay for Intracellular Apoptosis Activity using the Biomek Assay Workstation {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	Automation of the assay is achieved using the Biomek Assay Workstation with a Biomek NX integrated with a Cytomat* incubator and storage carousel for cell preparation, apoptosis induction and detection.
Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	Authors: Michael P. Kowalski \| Vipat Raksakulthai \| Kristin Prasauckas \| Tara Jones-Roe

Biomek FXᴾ Automated Workstation

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